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born, such as the appearance of microcephaly and other abnormalities. Recent studies have shown that ZIKV predominantly infects neural stem and progenitor cells NPCs and disrupts key processes, such as survival, proliferation and differentiation, leading to massive cell death and growth reduction. At the operational level, the team is in a consolidation phase. At the Paoua hospital, for example, we need to organize the management of the pharmacy, set up a cold chain or even review the way in which medical spiron data is collected and compiled. Concerning the mobile dispensary, we need to make some adjustments to the places we visit, for example by building latrines and basic shelters for patients in the event of rain. We also need to plan the logistical organization of transport and installation on each site. This phase 3 study presents the first data demonstrating the effectiveness of the drug, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis.
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