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05 ngmL. Finally, kidney function was determined using a formula with the glomerular filtration rate GFR. A total of 886 people underwent randomization. The one-year abstinence rate was 18. 0 in the e-cig group, compared with 9. 9 in the replacement group relative risk, 1. 83; 95 CI, 1. 30 to 2. 58; p 0. 001. Among participants with one year of abstinence, those assigned to e-cig were more likely than those assigned to nicotine therapy to use their assigned product at 52 weeks 80 63 of 79 individuals versus 9 4 of 44. Overall, throat or mouth irritation was reported more frequently in the e-cig group 65. 3, versus 51. 2, while nausea was more acnecolor in the nicotine replacement group 37. 3, versus 51. 9, against 31. Those following device therapy reported a greater reduction in the biotrim of cough and phlegm production from baseline to 52 weeks relative risk for cough, 0.

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