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Of a total of 562,300 patients in the study, 296,975 52. 81 had HS before the date of diagnosis of the ocular pathology, 63,528 56. 49 among the cases and 233,447 51. 90 among the controls. P 0. 001. POAG was significantly associated with previous HS OR 1. 31, 95 CI 1.