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Literature is also accumulating regarding the potential non-cardiovascular benefits of statins, which could lead to new applications in the future. The therapy is directed at liver cells and aimed at reducing the levels of aminolevulinic acid synthase 1, the first enzyme in the heme biosynthetic pathway. According to the World Health Organization WHO, 450 million people worldwide suffer from at least one mental disorder. 85 live in low- and middle-income countries. The lack of access to treatment is immense. In the event of war or natural disaster, the rate of people suffering from common mental disorders, such as depression or anxiety, can reach 25 to 30, or two or three times more than in normal times.
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