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Heterozygous carriers of the mutation 1 in 120 people in the study population had a lower level of non-HDL cholesterol than noncarriers, a difference of 15. 3 mg per deciliter 0. 40 mmol per liter P 1. 0 x 10 -16, and a lower chance of having coronary artery disease by 34; 95 CI 21 - 45; P 4.