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The present publication reports the results of two double-blind randomized controlled trials, which included outpatients with acute non-complex influenza. After a first trial using placebo as a control 10 to 40 mg, a second placebo- and oseltamivir-controlled study was conducted to evaluate the efficacy of single doses of baloxavir 40 or 80 mg in patients aged 12 to 64 years. age during the 2016 - 2017 season. The dose of oseltamivir was 75 mg twice a day for 5 days. The primary efficacy endpoint was time to relief of influenza symptoms in the population using intention-to-treat analysis.
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