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These studies included adults aged 19 to 99 years with spontaneous non-traumatic intracerebral hemorrhage and elevated systolic BP, without a clear indication or contraindication for treatment. Subjects were excluded if they had a structural brain cause for the hemorrhage, had a low score 3 - 5 on the Glasgow Coma Scale, or required immediate neurosurgery. The primary analysis assessed independent associations between three postrandomization summary measures of systolic BP magnitude of reduction at 1 hour, mean systolic BP achieved, and variability of systolic BP between 1 h and 24 h and the primary outcome measure of functional status, as defined by the distribution of scores on the modified Rankin Scale at 90 days after randomization.

Systolic BP measures were analyzed as continuous variables using generalized linear mixed models, adjusted for baseline covariates. Primary and safety analyzes were performed in a modified intention-to-treat population, which only included individuals with sufficient blood pressure data. Monitoring and evaluation. The southwest of the CAR is a diamond-rich region. But this activity has been in crisis for several months, and several purchasing offices in the city have had to close their doors. However, this economic slowdown is not enough to explain the emergence of a worrying nutritional situation.

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