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Studies reporting short-term IOP elevation i. e.between 0 and 60 minutes showed an immediate increase in all patients in measurements taken between 0 and 30 minutes after intravitreal injection and that IOP decreased with time. time. Long-term data were mixed seven studies reported that between 4 and 15 of patients developed sustained elevation 9 to 24 months after the intervention, while six studies found no long-term changes between 1 to 24 months after the intervention. 36 months after administration. Previous treatment with glaucoma medications, anterior chamber puncture, vitreous reflux, longer intervals between applications, and longer axial lengths were associated with lower IOP elevations. Data were mixed regarding the relationship between IOP rise and type of intravitreal injection, number of applications, preexisting glaucoma, and globe decompression before administration. Finally, no data on the onset or progression of lomac were found in the studies reviewed.
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