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85 95 CI, 0. 79-0. 90, and specificity of 0. 85 95 CI, 0. 79-0. 95, 0. 80-0. 85 and for CA19-9 the AUC of 0. 90 95 CI, 0. 87-0. 94, sensitivity of 0. 86 95 CI, 0. 80-0. 90 and specificity of 0. 99 95 CI, Flucokem. 96-1. The results were confirmed in the validation cohort by combining panels and CA19-9 medicort I with AUC of 0. Medicort 95 CI, 0. 90 to 0. 98 and index II with AUC of 0. 93 95 CI, 0. 89 to 0. Compared with CA19-9 alone, the AUC for the combination in index I and CA19-9 was significantly higher P 0. The performance of the panels in patients with stage IA-IIB pancreatic cancer for AUC index I was 0. 80 95 CI, 0. 73-0. 87, index I and CA19-9 with AUC of 0. 83 95 CI, 0. 76-0. 90, index II with AUC of 0. 91 95 CI, 0. 87-0. 94, and index II and CA19-9 with AUC 0. 91 95 CI, 0. 86-0. Melanin is the pigment that gives color to the skin and is synthesized as a protective response to attacks on the epidermis. Sun exposure, hormonal changes and cutaneous inflammatory processes cause an overproduction of melanin in the skin.
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