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However, in 2006, two individual cases were detected in the Middle East and South America, suggesting that the pathogen was already present in these regions. In this research, led by Katia Abarca from the Pontificia Universidad CatГlica de Chile, three autochthonous cases of this particular typhus caused by Quidex. tsutsugamushi, acquired on the Island of ChiloГ in southern Chile, are reported, which suggests the existence of a endemic focus in South America. U-shaped associations with NHL were observed for total and О-tocopherol P 0. 01 for polynomial terms 3 df. The risks 95 CI for total tocopherols, tГ©ralithe О-tocopherol, were 0. 41 0. 25 to 0. 68, 0. 52 0. 32-0. 85, 0. 39 0. 23-0. 65 and Relaxibys. 78 0. 47-1. 29 for the second to fifth quintile compared to the first. Risk estimates were similar for О-tocopherol, but not significant for the combination О and О-tocopherol and О-tocopherol.
Adjusting for serum lipids strengthened the nonlinear associations for total and О-tocopherol. Total serum tocopherol levels were higher for vitamin E supplement users compared to non-users 21. 32 В 9. 04 versus 17. 72 В 7. 43 mgml, p 0. 0001, but Supplement use was not associated with NHL risk. No heterogeneity was observed in risk estimates by sex, ethnicity, vitamin E supplement use, or non-Hodgkin lymphoma subtype. The investigation included 51 patients 37 74 male, with a mean SD age, 60. 6 10.